Detalhe da pesquisa
1.
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Cell
; 182(4): 976-991.e19, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32702314
2.
Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10.
Nat Immunol
; 18(3): 313-320, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28068307
3.
Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy.
Mol Cell
; 50(6): 831-43, 2013 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23685073
4.
PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402.
J Biol Chem
; 290(5): 2798-811, 2015 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25527497
5.
Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins.
iScience
; 27(4): 109136, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38510136
6.
Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer's Disease Brains and Mouse Neurodegeneration Models.
eNeuro
; 10(1)2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599670
7.
MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Science
; 381(6663): 1176-1182, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37708272
8.
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.
Nat Neurosci
; 26(6): 1021-1031, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188873
9.
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.
Cell Rep
; 40(8): 111280, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001964
10.
The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.
J Neurosci
; 30(14): 4833-44, 2010 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371803
11.
Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Cell Stem Cell
; 28(10): 1805-1821.e8, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34033742
12.
The two faces of synaptic failure in AppNL-G-F knock-in mice.
Alzheimers Res Ther
; 12(1): 100, 2020 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32838792
13.
Neuronal membrane cholesterol loss enhances amyloid peptide generation.
J Cell Biol
; 167(5): 953-60, 2004 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15583033
14.
Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency.
J Cell Biol
; 216(3): 695-708, 2017 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137779
15.
No endogenous A beta production in presenilin-deficient fibroblasts.
Nat Cell Biol
; 4(7): E164; author reply E165-6, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12105423
16.
In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues.
PLoS One
; 11(1): e0146083, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26784449
17.
PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.
Science
; 344(6180): 203-7, 2014 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24652937
18.
Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains.
Nat Cell Biol
; 11(11): 1340-6, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19838174
19.
gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
Science
; 324(5927): 639-42, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19299585
20.
Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes.
EMBO Rep
; 7(7): 739-45, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16729020